Article
Human apolipoprotein A-I gene promoter mutation influences plasma low density lipoprotein cholesterol response to dietary fat saturation.
Atherosclerosis - 1 Apr 1998
Mata P, Lopez-Miranda J, Pocovi M, Alonso R, Lahoz C, Marin C, Garces C, Cenarro A, Perez-Jimenez F, de Oya M, Ordovas J M
Abstract excerpt
Previous studies have shown that the A to G transition occurring at position -75 bp upstream of the transcriptional start site in the human apolipoprotein A-I gene may affect plasma high density lipoprotein cholesterol (HDL-C) levels and low density lipoprotein cholesterol (LDL-C) response to changes in amount of dietary fat. We have examined the response to dietary fat saturation as a function of this mutation...
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