Isolation of quelling-defective (qde) mutants impaired in posttranscriptional transgene-induced gene silencing in Neurospora crassa.

doi:10.1073/pnas.94.19.10233

Back to search

Article

Isolation of quelling-defective (qde) mutants impaired in posttranscriptional transgene-induced gene silencing in Neurospora crassa.

Proceedings of the National Academy of Sciences of the United States of America - 16 Sept 1997

Cogoni C, Macino G

Abstract excerpt

We report the isolation of 15 Neurospora crassa mutants defective in "quelling" or transgene-induced gene silencing. These quelling-defective mutants (qde) belonging to three complementation groups have provided insights into the mechanism of posttranscriptional gene silencing in N. crassa. The r...

Topics

Genes, Fungal
Genes, Recessive
Genetic Complementation Test
Mutation
Neurospora crassa
RNA Processing, Post-Transcriptional
Transgenes

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.