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Article

Gene silencing: RNA makes RNA makes no protein.

Current biology : CB - 26 Aug 1999

Baulcombe D C

Abstract excerpt

A mutation that disrupts post-transcriptional gene silencing in Neurospora crassa has been found to affect the homologue of a plant-encoded RNA-dependent RNA polymerase. This enzyme may produce a specificity determinant of gene silencing and mediate an epigenetic conversion at the RNA level.

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Source

Identifiers

PMID: 10469584
DOI: 10.1016/s0960-9822(99)80383-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Gene silencing: RNA makes RNA makes no protein.PMID 10469584Read ↗

Post-transcriptional gene silencing mutants.Semantic proximity Read ↗

DNA methylation is independent of RNA interference in Neurospora.Semantic proximity Read ↗

Post-transcriptional gene silencing: conservation and sequences.Semantic proximity Read ↗

Protecting genes from RNA silencing by destroying aberrant transcripts.Semantic proximity Read ↗

Gene expression: long-term gene silencing by RNAi.Semantic proximity Read ↗

Down-regulation of gene expression by RNA-induced gene silencing.Semantic proximity Read ↗

Non-cell autonomous RNA silencing.Semantic proximity Read ↗

Small interfering RNAs that trigger posttranscriptional gene silencing are not required for the histone H3 Lys9 methylation necessary for transgenic tandem repeat stabilization in Neurospora crassa.Semantic proximity Read ↗

Characteristics of post-transcriptional gene silencing.Semantic proximity Read ↗

The RNA-dependent RNA polymerase, QDE-1, is a rate-limiting factor in post-transcriptional gene silencing in Neurospora crassa.Semantic proximity Read ↗

Dominant suppression of repeat-induced point mutation in Neurospora crassa by a variant catalytic subunit of DNA polymerase zeta.Semantic proximity Read ↗

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