Article
Down-regulation of gene expression by RNA-induced gene silencing.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2009
Travella Silvia, Keller Beat
Abstract excerpt
Down-regulation of endogenous genes via post-transcriptional gene silencing (PTGS) is a key to the characterization of gene function in plants. Many RNA-based silencing mechanisms such as post-transcriptional gene silencing, co-suppression, quelling, and RNA interference (RNAi) have been discovered among species of different kingdoms (plants, fungi, and animals). One of the most interesting discover ies was RNAi,...
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