Article
MHC class II genes influence the susceptibility to chronic active hepatitis C.
Journal of hepatology - 1 Aug 1997
Höhler T, Gerken G, Notghi A, Knolle P, Lubjuhn R, Taheri H, Schneider P M, Meyer zum Büschenfelde K H, Rittner C
Abstract excerpt
BACKGROUND/AIMS: Chronic hepatitis C develops in more than 70% of hepatitis C virus infected subjects. Viral factors influence the disease course, but little is known about the importance of host factors. METHODS: Frequencies of major histocompatibility complex (MHC) class I and class II antigens were analyzed in two groups of patients with chronic hepatitis C virus infection and in control subjects. MHC class I...
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