Article
Protective effect of HLA-DRB1 11 and predisposition of HLA-C 04 in the development of severe liver damage in Brazilian patients with chronic hepatitis C virus infection.
Scandinavian journal of immunology - 1 Oct 2012
Marangon A V, Silva G F, de Moraes C F V, Grotto R M T, Pardini M I M C, de Pauli D S, Visentainer J E L, Sell A M, Moliterno R A
Abstract excerpt
The objective of this study was to investigate human leucocyte antigen (HLA) genes in patients chronically infected with hepatitis C virus (HCV) and to analyse the possible role of these genes in the progression of chronic hepatitis C. One hundred and forty-five (145) Brazilian patients infected only with HCV genotype 1 were evaluated. HLA class I (A, B, C) and class II (DRB1, DQA1, DQB1) typing were carried out...
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