Article
HLA class II alleles and chronic hepatitis C virus infection.
Scandinavian journal of immunology - 1 Sept 2011
Cangussu L O F, Teixeira R, Campos E F, Rampim G F, Mingoti S A, Martins-Filho O A, Gerbase-DeLima M
Abstract excerpt
The aim of this study was to investigate association of human leucocyte antigens (HLA)-DRB1 and DQB1 polymorphisms with hepatitis C virus (HCV) infection and with the occurrence of severe liver fibrosis/cirrhosis in chronically infected patients. Ninety-nine white patients, from southeast Brazil, with confirmed HCV chronic infection were included in the study. Severe fibrosis/cirrhosis (METAVIR scores F3-F4) was...
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