Article
Active immunization using dendritic cells mixed with tumor cells inhibits the growth of primary breast cancer.
Surgery - 1 Aug 1997
Coveney E, Wheatley G H, Lyerly H K
Abstract excerpt
BACKGROUND: Dendritic cells (DCs) are potent antigen-presenting cells regarded as crucial in the priming of an immune response. The goal of our study was to test whether bone marrow-generated DCs are capable of inducing protective immunity against a murine breast carcinoma (4T1). METHODS: DCs were grown from Balb/c mice by culturing lymphocyte-immunodepleted bone marrow in murine granulocyte-macrophage...
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