Article
The TNF-α Gene <i>Neo</i> I Polymorphism Influences the Relationship Among Insulin Resistance, Percent Body Fat, and Increased Serum Leptin Levels
1 Sept 1997
Abstract excerpt
Tumor necrosis factor-alpha (TNF-alpha), acting as a modulator of gene expression in adipocytes, is implicated in the development of insulin resistance and obesity. The aim of this study was to investigate whether the Nco I polymorphism of the TNF-alpha gene influences the relationship among insulin resistance, percent body fat, and serum leptin levels. A sample of 38 subjects (19 men, mean age 36.2 +/- 1.9...
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