Article
Rapid chondrocyte maturation by serum-free culture with BMP-2 and ascorbic acid.
Journal of cellular biochemistry - 1 Sept 1997
Leboy P S, Sullivan T A, Nooreyazdan M, Venezian R A
Abstract excerpt
In serum-containing medium, ascorbic acid induces maturation of prehypertrophic chick embryo sternal chondrocytes. Recently, cultured chondrocytes have also been reported to undergo maturation in the presence of bone morphogenetic proteins or in serum-free medium supplemented with thyroxine. In the present study, we have examined the combined effect of ascorbic acid, BMP-2, and serum-free conditions on the...
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