Article
Reliability, robustness, and reproducibility in mouse behavioral phenotyping: a cross-laboratory study.
Physiological genomics - 15 Aug 2008
Mandillo Silvia, Tucci Valter, Hölter Sabine M, Meziane Hamid, Banchaabouchi Mumna Al, Kallnik Magdalena, Lad Heena V, Nolan Patrick M, Ouagazzal Abdel-Mouttalib, Coghill Emma L, Gale Karin, Golini Elisabetta, Jacquot Sylvie, Krezel Wojtek, Parker Andy, Riet Fabrice, Schneider Ilka, Marazziti Daniela, Auwerx Johan, Brown Steve D M, Chambon Pierre, Rosenthal Nadia, Tocchini-Valentini Glauco, Wurst Wolfgang
Abstract excerpt
Establishing standard operating procedures (SOPs) as tools for the analysis of behavioral phenotypes is fundamental to mouse functional genomics. It is essential that the tests designed provide reliable measures of the process under investigation but most importantly that these are reproducible across both time and laboratories. For this reason, we devised and tested a set of SOPs to investigate mouse behavior....
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