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Article

Inefficient secretion of human H27A-prolactin, a mutant that does not bind Zn2+.

Molecular endocrinology (Baltimore, Md.) - 1 Sept 1997

Sun Z, Lee M S, Rhee H K, Arrandale J M, Dannies P S

Abstract excerpt

Human PRL binds Zn2+, but the function of the binding is not known. We investigated the effect on PRL production in pituitary cells by obtaining clones of GH4C1 cells stably transfected with human H27A-PRL, a mutant that does not bind Zn2+. Unexpectedly, clones transfected with the mutant human P...

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PMID: 9280069
DOI: 10.1210/mend.11.10.0002

Genes

PRL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-9280069-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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