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Article

Abnormal glutathione conjugation in patients with tyrosinaemia type I.

Journal of inherited metabolic disease - 1 Aug 1997

Mulders T M, Bergman D J, Poll-The B T, Smit G P, Breimer D D, Mulder G J, Duran M, Smeitink J A

Abstract excerpt

Previous studies have suggested that tyrosinaemia type I may be associated with reduced glutathione availability due to conjugation of tyrosinaemia-associated reactive intermediates with glutathione. In the present study, the glutathione/ glutathione S-transferase system of two tyrosinaemia patients and three healthy controls were characterized by administering the racemic sedative drug bromisoval, a probe drug...

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Identifiers

PMID: 9266383
DOI: 10.1023/a:1005385009831

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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