Article
Inhibition of the human erythrocytic glutathione-S-transferase T1 (GST T1) by thimerosal.
International journal of hygiene and environmental health - 1 Jul 2001
Müller M, Westphal G, Vesper A, Bünger J, Hallier E
Abstract excerpt
We have investigated the interaction of thimerosal, a widely used antiseptic and preservative, with the human erythrocytic GST T1 (glutathione-S-transferase T1). This detoxifying enzyme is expressed in the erythrocytes of solely the human species and it displays a genetic polymorphism. Due to this polymorphism about 25% of the individuals of the caucasian population lack this activity ("non-conjugators"), while...
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