Article
Modulation of immune response following dietary genistein exposure in F0 and F1 generations of C57BL/6 mice: evidence of thymic regulation.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association - 1 Mar 2006
Guo T L, Chi R P, Zhang X L, Musgrove D L, Weis C, Germolec D R, White K L
Abstract excerpt
To further determine whether genistein (GEN) modulation of the immune responses was related to its endocrine-disrupting properties and time of exposure, pregnant C57BL/6 mice were exposed to GEN at 0-1250 ppm in feed starting on day 14 of gestation. The C57BL/6 offspring were exposed to GEN in utero and lactationally, and through feed after weaning until postnatal day 42. In dams, exposure to GEN increased the...
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