Article
Aberrant reproductive phenotypes evident in transgenic mice expressing the wild-type mouse estrogen receptor.
Endocrinology - 1 Jul 1994
Davis V L, Couse J F, Goulding E H, Power S G, Eddy E M, Korach K S
Abstract excerpt
The estrogen receptor (ER) acts as a transcription factor to regulate multiple cellular functions involved in normal physiology, differentiation, and reproduction. To date, there is no known animal model for studying aberrant ER expression. Therefore, we created transgenic mice expressing the wil...
Topics
- Animals
- Female
- Genetic Techniques
- Male
- Mice
- Mice, Transgenic
- Phenotype
- Receptors, Estrogen
- Reproduction