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Article

HIV phenotype switching during antiretroviral therapy: emergence of saquinavir-resistant strains with less cytopathogenicity.

AIDS (London, England) - 1 Aug 1997

Ercoli L, Sarmati L, Nicastri E, Giannini G, Galluzzo C, Vella S, Andreoni M

Abstract excerpt

OBJECTIVES: The aim of the study was to investigate changes in virological characteristics of HIV strains isolated from 38 HIV-seropositive subjects during antiretroviral therapy. DESIGN AND METHODS: Patients with a CD4+ cell count < or = 300 x 10(6)/l were treated with zidovudine (12 individuals) and saquinavir (10 individuals) alone or in combination (16 individuals). CD4+ cell count, viral load, HIV biological...

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Identifiers

PMID: 9256938
DOI: 10.1097/00002030-199710000-00003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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