Changes in cellular virus load and zidovudine resistance of syncytium-inducing and non-syncytium-inducing human immunodeficiency virus populations under zidovudine pressure: a clonal analysis.

doi:10.1093/infdis/174.4.845

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Article

Changes in cellular virus load and zidovudine resistance of syncytium-inducing and non-syncytium-inducing human immunodeficiency virus populations under zidovudine pressure: a clonal analysis.

The Journal of infectious diseases - 1 Oct 1996

van 't Wout A B, de Jong M D, Kootstra N A, Veenstra J, Lange J M, Boucher C A, Schuitemaker H

Abstract excerpt

Zidovudine treatment preferentially benefits persons with only non-syncytium-inducing (NSI) human immunodeficiency virus type 1 (HIV-1) variants. To understand this differential efficacy, changes in cellular virus load, clonal composition of HIV-1 populations, and development of resistance-confer...

Topics

Acquired Immunodeficiency Syndrome
Anti-HIV Agents
Drug Resistance
HIV-1
Humans
Male
Mutation
Zidovudine

Source

Open in PubMed

Identifiers

PMID: 8843227
DOI: 10.1093/infdis/174.4.845

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8843227-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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