[GH receptor gene mutations and growth failure].

Article

[GH receptor gene mutations and growth failure].

Nihon rinsho. Japanese journal of clinical medicine - 1 Jul 1998

Kaji H

Abstract excerpt

Abnormality of growth hormone (GH) receptor (GHR) and signal transduction system is a cause of primary GH insensitivity. Analysis of GHR gene have shown so far about 30 different kinds of mainly homozygous mutations in patients with Laron syndrome and heterozygous mutations in some patients with...

Topics

Genotype
Growth Disorders
Humans
Mutation
Receptors, Somatotropin
Signal Transduction
Syndrome

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