Article
Phylogenetic reconstruction of vertebrate Hox cluster duplications.
Molecular biology and evolution - 1 Aug 1997
Bailey W J, Kim J, Wagner G P, Ruddle F H
Abstract excerpt
In vertebrates and the cephalochordate, amphioxus, the closest vertebrate relative, Hox genes are linked in a single cluster. Accompanying the emergence of higher vertebrates, the Hox gene cluster duplicated in either a single step or multiple steps, resulting in the four-cluster state present in teleosts and tetrapods. Mammalian Hox clusters (designated A, B, C, and D) extend over 100 kb and are located on four...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
