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Molecular evolution of fibrillar collagen in chordates, with implications for the evolution of vertebrate skeletons and chordate phylogeny

28 Jun 2006

Abstract excerpt

Vertebrates have seven types of fibrillar collagens that are encoded by 11 genes. Types I, V, and XXIV collagens are components of mineralized bone, whereas types II, XI, and XXVII collagens are components of cartilage. In this study, we traced the molecular evolutionary history of chordate collagen genes and examined how gene duplications gave rise to the collagen genes used for skeletons. Our analyses of...

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PMID: 16805901
DOI: 10.1111/j.1525-142x.2006.00109.x

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