Article
Organization of the Fugu rubripes Hox clusters: evidence for continuing evolution of vertebrate Hox complexes.
Nature genetics - 1 May 1997
Aparicio S, Hawker K, Cottage A, Mikawa Y, Zuo L, Venkatesh B, Chen E, Krumlauf R, Brenner S
Abstract excerpt
The clustered organization of Hox genes provides a powerful opportunity to examine gene gain and loss in evolution because physical linkage is a key diagnostic feature which allows homology to be established unambiguously. Furthermore, Hox genes play a key role in determination of axial and appen...
Topics
- Amino Acid Sequence
- Animals
- Cloning, Molecular
- Conserved Sequence
- DNA-Binding Proteins
- Evolution, Molecular
- Fishes, Poisonous
- Genes, Homeobox
- Genetic Linkage
- Genetic Variation
- Homeodomain Proteins
- In Situ Hybridization
- Molecular Sequence Data
- Multigene Family
- Polymerase Chain Reaction