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Article

Identification of unique α4 chain structure and conserved anti-angiogenic activity of α3NC1 type IV collagen in zebrafish

2022-08-15

Abstract excerpt

Type IV collagen is an abundant component of basement membranes in all multicellular species and is essential for the extracellular scaffold supporting tissue architecture and function. Lower organisms typically have two type IV collagen genes, encoding α1 and α2 chains, in contrast with the six genes in humans, encoding α1 to α6 chains. The α chains assemble into trimeric protomers, the building blocks of the typ...

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Identifiers and source

Literature Corpus work
c4152b6d-ce1d-52bc-8c21-5f83b5c50831
DOI
10.1101/2022.08.14.503918
Open publication

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Identification of unique α4 chain structure and conserved anti-angiogenic activity of α3NC1 type IV collagen in zebrafishDOI 10.1101/2022.08.14.503918
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