Article
Subcellular localization of the major autolysin, ATL and its processed proteins in Staphylococcus aureus.
Microbiology and immunology - 1 Jan 1997
Komatsuzawa H, Sugai M, Nakashima S, Yamada S, Matsumoto A, Oshida T, Suginaka H
Abstract excerpt
The Staphylococcus aureus autolysin gene, atl, encodes a unique 138-kDa protein (ATL) with amidase and glucosaminidase domains. ATL has been suggested to undergo proteolytic processing to generate two extracellular peptidoglycan hydrolases, 51-kDa endo-beta-N-acetylglucosaminidase (51-kDa GL) and 62-kDa N-acetylmuramyl-L-alanine amidase (62-kDa AM). To investigate cell-associated bacteriolytic enzymes for atl...
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