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Article

Localized perforation of the cell wall by a major autolysin: atl gene products and the onset of penicillin-induced lysis of Staphylococcus aureus.

Journal of bacteriology - 1 May 1997

Sugai M, Yamada S, Nakashima S, Komatsuzawa H, Matsumoto A, Oshida T, Suginaka H

Abstract excerpt

We investigated the cell surface localization of the atl gene products of Staphylococcus aureus exposed to a lytic concentration (4 MIC) of penicillin G (PCG) by means of immunoelectron microscopy using anti-62-kDa N-acetylmuramyl-L-alanine amidase or anti-51-kDa endo-beta-N-acetylglucosaminidase immunoglobulin G. Protein A-gold conjugates reacting with antigen-antibody complex localized at sites of defects of...

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Identifiers

PMID: 9139914
DOI: 10.1128/jb.179.9.2958-2962.1997
PMCID: PMC179060

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