Article
Characterization of the modular design of the autolysin/adhesin Aaa from Staphylococcus aureus.
PloS one - 1 Jan 2012
Hirschhausen Nina, Schlesier Tim, Peters Georg, Heilmann Christine
Abstract excerpt
BACKGROUND: Staphylococcus aureus is a frequent cause of serious and life-threatening infections, such as endocarditis, osteomyelitis, pneumonia, and sepsis. Its adherence to various host structures is crucial for the establishment of diseases. Adherence may be mediated by a variety of adhesins, among them the autolysin/adhesins Atl and Aaa. Aaa is composed of three N-terminal repeated sequences homologous to a...
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