<i>Streptococcus mutans</i> autolysin AtlA is a fibronectin‐binding protein and contributes to bacterial survival in the bloodstream and virulence for infective endocarditis

Abstract excerpt

Streptococcus mutans, a commensal of the human oral cavity, can survive in the bloodstream and cause infective endocarditis (IE). However, the virulence factors associated with this manifestation of disease are not known. Here, we demonstrate that AtlA, an autolysin of S. mutans is a newly identified fibronectin (Fn) binding protein and contributes to bacterial resistance to phagocytosis and survival in the...

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