Article
Atopy phenotype in subjects with variants of the beta subunit of the high affinity IgE receptor.
Thorax - 1 Jul 1997
Li A, Hopkin J M
Abstract excerpt
BACKGROUND: Fc epsilon RI plays a central role in atopy, thus genetic variants of Fc epsilon RI-beta may alter receptor function to enhance atopic responses and may manifest as a more severe atopic phenotype and more symptomatic atopic disease. The immunological and clinical features of atopy in children with and without the Leu 181 variant of Fc epsilon RI-beta were compared. METHODS: Sixty British nuclear...
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