Atopy phenotype in subjects with variants of the beta subunit of the high affinity IgE receptor.

doi:10.1136/thx.52.7.654

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Article

Atopy phenotype in subjects with variants of the beta subunit of the high affinity IgE receptor.

Thorax - 1 Jul 1997

Li A, Hopkin J M

Abstract excerpt

BACKGROUND: Fc epsilon RI plays a central role in atopy, thus genetic variants of Fc epsilon RI-beta may alter receptor function to enhance atopic responses and may manifest as a more severe atopic phenotype and more symptomatic atopic disease. The immunological and clinical features of atopy in...

Topics

Adolescent
Adult
Child
Child, Preschool
Chromosomes, Human, Pair 11
Female
Genotype
Humans
Hypersensitivity, Immediate
Immunoglobulin E
Linkage Disequilibrium
Male
Mutation
Phenotype
Receptors, IgE
Sequence Analysis, DNA

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