Article
ADP ribosylation factor 1 is required for synaptic vesicle budding in PC12 cells.
The Journal of cell biology - 11 Aug 1997
Faúndez V, Horng J T, Kelly R B
Abstract excerpt
Carrier vesicle generation from donor membranes typically progresses through a GTP-dependent recruitment of coats to membranes. Here we explore the role of ADP ribosylation factor (ARF) 1, one of the GTP-binding proteins that recruit coats, in the production of neuroendocrine synaptic vesicles (SVs) from PC12 cell membranes. Brefeldin A (BFA) strongly and reversibly inhibited SV formation in vivo in three...
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