Article
Poliovirus proteins induce membrane association of GTPase ADP-ribosylation factor.
Journal of virology - 1 Jun 2005
Belov George A, Fogg Mark H, Ehrenfeld Ellie
Abstract excerpt
Poliovirus infection results in the disintegration of intracellular membrane structures and formation of specific vesicles that serve as sites for replication of viral RNA. The mechanism of membrane rearrangement has not been clearly defined. Replication of poliovirus is sensitive to brefeldin A (BFA), a fungal metabolite known to prevent normal function of the ADP-ribosylation factor (ARF) family of small...
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