Article
Ankyrin binding mediates L1CAM interactions with static components of the cytoskeleton and inhibits retrograde movement of L1CAM on the cell surface.
The Journal of cell biology - 18 Aug 2003
Gil Orlando D, Sakurai Takeshi, Bradley Ann E, Fink Marc Y, Cassella Melanie R, Kuo James A, Felsenfeld Dan P
Abstract excerpt
The function of adhesion receptors in both cell adhesion and migration depends critically on interactions with the cytoskeleton. During cell adhesion, cytoskeletal interactions stabilize receptors to strengthen adhesive contacts. In contrast, during cell migration, adhesion proteins are believed to interact with dynamic components of the cytoskeleton, permitting the transmission of traction forces through the...
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