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Article

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity.

Nature - 24 Jul 1997

Medzhitov R, Preston-Hurlburt P, Janeway C A

Abstract excerpt

Induction of the adaptive immune response depends on the expression of co-stimulatory molecules and cytokines by antigen-presenting cells. The mechanisms that control the initial induction of these signals upon infection are poorly understood. It has been proposed that their expression is control...

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PMID: 9237759
DOI: 10.1038/41131

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9237759-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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