[Role and function of voltage-gated chloride channels of the CIC family and their defects leading to genetic diseases].

Abstract excerpt

There are 9 channels of the ClC family in mammals and few others in fishes, plants, yeast and bacteria. The ClC channels are present in different tissues and play a role in transmembrane potential stabilization, transepithelial transport, cell volume regulation, acidification of intracellular organelles. The genetic defects of ClC-1 chloride channel lead to myotonias, the defect in ClC-5 channel to the formation...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bartter Syndrome
• Share to Chloride Channels