Article
[Selection of resistance mutants and bacteriostatic and bactericidal activity of meropenem and imipenem against Acinetobacter spp].
Enfermedades infecciosas y microbiologia clinica - 1 Mar 1997
Villar H E, Laurino G, Arena M F, Hoffman M
Abstract excerpt
BACKGROUND: To evaluate the inhibitory and bactericidal activity of meropenem and imipenem against multiresistant isolates of Acinetobacter spp and to compare the frequency of mutation for both antibiotics. METHODS: Minimum inhibitory concentrations were determined by the agar dilution method. Bactericidal activities were evaluated by killing curves method employing 8 times the MIC. One-step resistant mutant...
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