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Article

Imipenem: a potent inducer of multidrug resistance in Acinetobacter baumannii.

International journal of antimicrobial agents - 1 Jan 2012

Kuo Han-Yueh, Chang Kai-Chih, Kuo Jai-Wei, Yueh Hui-Wen, Liou Ming-Li

Abstract excerpt

This study investigated the progression of multidrug resistance upon exposure to imipenem in Acinetobacter baumannii. Eighteen A. baumannii strains, including two reference strains (ATCC 19606 and ATCC 17978), four clinical strains (AB56, AB242, AB273 and AB279) and 12 antibiotic-selected mutant strains, were used in this study. Imipenem-selected mutants were generated from imipenem-susceptible strains (ATCC...

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Identifiers

PMID: 21996406
DOI: 10.1016/j.ijantimicag.2011.08.016

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