Article
In vitro susceptibility of four antimicrobials against Riemerella anatipestifer isolates: a comparison of minimum inhibitory concentrations and mutant prevention concentrations for ceftiofur, cefquinome, florfenicol, and tilmicosin.
BMC veterinary research - 9 Nov 2016
Li Yafei, Zhang Yanan, Ding Huanzhong, Mei Xian, Liu Wei, Zeng Jiaxiong, Zeng Zhenling
Abstract excerpt
BACKGROUND: Mutant prevention concentration (MPC) is an alternative pharmacodynamic parameter that has been used to measure antimicrobial activity and represents the propensities of antimicrobial agents to select resistant mutants. The concentration range between minimum inhibitory concentration (MIC) and MPC is defined as mutant selection window (MSW). The MPC and MSW parameters represent the ability of...
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