The mesodermal expression of rolling stone (rost) is essential for myoblast fusion in Drosophila and encodes a potential transmembrane protein.

doi:10.1083/jcb.138.2.337

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Article

The mesodermal expression of rolling stone (rost) is essential for myoblast fusion in Drosophila and encodes a potential transmembrane protein.

The Journal of cell biology - 28 Jul 1997

Paululat A, Goubeaud A, Damm C, Knirr S, Burchard S, Renkawitz-Pohl R

Abstract excerpt

In homozygous rolling stone embryos, the fusion of myoblasts to syncytial myotubes is diminished. Nevertheless, the visceral mesoderm, the heart mesoderm, and few somatic muscles are properly formed. Thus, we postulate a central role of rolling stone for the fusion process within the somatic meso...

Topics

Amino Acid Sequence
Animals
Base Sequence
Cell Fusion
Cloning, Molecular
Drosophila
Drosophila Proteins
Ectoderm
Gene Expression Regulation, Developmental
Genes, Insect
Membrane Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mesoderm

Molecular Sequence Data

Muscle Fibers, Skeletal

Muscle Proteins

Muscles

Mutation

Nervous System

Source

Open in PubMed Open full text

Identifiers

PMID: 9230076
DOI: 10.1083/jcb.138.2.337
PMCID: PMC2138187

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9230076-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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The mesodermal expression of rolling stone (rost) is essential for myoblast fusion in Drosophila and encodes a potential transmembrane protein.PMID 9230076Read ↗

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