Article
rolling pebbles (rols) is required in Drosophila muscle precursors for recruitment of myoblasts for fusion.
Development (Cambridge, England) - 1 Dec 2001
Rau A, Buttgereit D, Holz A, Fetter R, Doberstein S K, Paululat A, Staudt N, Skeath J, Michelson A M, Renkawitz-Pohl R
Abstract excerpt
Mutations in the rolling pebbles (rols) gene result in severe defects in myoblast fusion. Muscle precursor cells are correctly determined, but myogenesis does not progress significantly beyond this point because recognition and/or cell adhesion between muscle precursor cells and fusion-competent myoblasts is disturbed. Molecular analysis of the rols genomic region reveals two variant transcripts of rols due to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.