Article
Association of DM genes in systemic sclerosis is secondary to the association with HLA genes.
Scandinavian journal of rheumatology - 1 Jan 1997
Takeuchi F, Takizawa K, Nabeta H, Kuwata S, Ito K
Abstract excerpt
The contribution of polymorphism of DMA and DMB alleles to the pathogenesis of Japanese Systemic Sclerosis (SSc) was studied in 55 Japanese SSc patients and 77 normal Japanese subjects using the PCR-RFLP (restriction fragment length polymorphism) method. The allele frequencies of DMB*0101 allele...
Topics
- Adult
- Aged
- Alleles
- DNA
- DNA Primers
- DNA Topoisomerases, Type I
- Female
- Genes, MHC Class II
- Genetic Predisposition to Disease
- HLA-D Antigens
- Histocompatibility Antigens Class II
- Humans
- Male
- Middle Aged
- Nuclear Proteins
- Phenotype
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length