Article
Induction of micronuclei by stilbene-type and steroidal estrogens in Syrian hamster embryo and ovine seminal vesicle cells in vitro.
Mutation research - 1 Nov 1994
Schnitzler R, Foth J, Degen G H, Metzler M
Abstract excerpt
The induction of micronuclei (MN) is a known effect of the carcinogenic estrogen diethylstilbestrol (DES). We have now tested the time course and dose dependence of MN induction by DES and its analogs 3',3"-DES, indenestrol A (IA), indenestrol B (IB) or by the steroidal estrogen 17 beta-estradiol...
Topics
- Animals
- Cells, Cultured
- Cricetinae
- Embryo, Mammalian
- Estrogens
- In Vitro Techniques
- Kinetics
- Kinetochores
- Male
- Mesocricetus
- Micronuclei, Chromosome-Defective
- Micronucleus Tests
- Mutation
- Seminal Vesicles
- Sheep
- Stilbenes
