Article
Up-regulation of nuclear genes in response to inhibition of mitochondrial DNA expression in chicken cells.
Biochimica et biophysica acta - 26 Jun 1997
Wang H, Morais R
Abstract excerpt
Vertebrate cells depleted of (rho0) mitochondrial DNA (mtDNA) exhibited phenotypic traits that differed from the parental (rho+) cells. To isolate genes whose expression is associated with mtDNA depletion, we constructed cDNA libraries from mRNAs isolated from chicken rho+ cells transformed by th...
Topics
- Actins
- Animals
- Blotting, Northern
- Cell Line, Transformed
- Chickens
- Chloramphenicol
- Cycloheximide
- DNA, Mitochondrial
- Dactinomycin
- Ethidium
- Genes, myc
- Peptide Elongation Factor 1
- Peptide Elongation Factors
- Phenotype
- RNA, Messenger
- Transcription, Genetic
- Up-Regulation