Article
Dolichol phosphate mannose synthase is required in vivo for glycosyl phosphatidylinositol membrane anchoring, O mannosylation, and N glycosylation of protein in Saccharomyces cerevisiae.
Molecular and cellular biology - 1 Nov 1990
Orlean P
Abstract excerpt
Glycosyl phosphatidylinositol (GPI) anchoring, N glycosylation, and O mannosylation of protein occur in the rough endoplasmic reticulum and involve transfer of precursor structures that contain mannose. Direct genetic evidence is presented that dolichol phosphate mannose (Dol-P-Man) synthase, whi...
Topics
- Carbohydrate Conformation
- Carbohydrate Sequence
- Chitinases
- Glycolipids
- Glycoside Hydrolases
- Glycosylation
- Glycosylphosphatidylinositols
- Mannosyltransferases
- Molecular Sequence Data
- Mutation
- Oligosaccharides
- Phosphatidylinositols
- Saccharomyces cerevisiae
- beta-Fructofuranosidase