Article
Apolipoprotein E epsilon4 allele decreases functional connectivity in Alzheimer's disease as measured by EEG coherence.
Journal of neurology, neurosurgery, and psychiatry - 1 Jul 1997
Jelic V, Julin P, Shigeta M, Nordberg A, Lannfelt L, Winblad B, Wahlund L O
Abstract excerpt
OBJECTIVES: The epsilon4 allele of apolipoprotein E (APOE) represents a major biological risk factor for late onset Alzheimer's disease. However, it is still not known whether the APOE genotype affects the progression of the disease, assessed by different functional methods. METHODS: The study sa...
Topics
- Age of Onset
- Aged
- Alleles
- Alpha Rhythm
- Alzheimer Disease
- Apolipoprotein E4
- Apolipoproteins E
- Cerebral Cortex
- Electroencephalography
- Female
- Functional Laterality
- Genotype
- Humans
- Male
- Middle Aged
- Theta Rhythm