Spectral analysis of EEG in Alzheimer's disease: relation to apolipoprotein E polymorphism.

doi:10.1016/0197-4580(96)00024-3

Back to search

Article

Spectral analysis of EEG in Alzheimer's disease: relation to apolipoprotein E polymorphism.

Neurobiology of aging - 1 Jan 2000

Lehtovirta M, Partanen J, Könönen M, Soininen H, Helisalmi S, Mannermaa A, Ryynänen M, Hartikainen P, Riekkinen P

Abstract excerpt

Apolipoprotein E (ApoE) epsilon 4 allele is a risk factor for late-onset Alzheimer's disease (AD) and proposed to have a direct impact on cholinergic function in AD. Slowing of the EEG is characteristic in AD and the cholinergic system has an important role in modulating EEG. Fifty-eight AD patie...

Topics

Aged
Alleles
Alzheimer Disease
Apolipoproteins E
Electroencephalography
Female
Humans
Male
Polymorphism, Genetic

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.