Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Patterns of meiotic variability of the (CAG)n repeat in the Huntington disease gene.

Genetic counseling (Geneva, Switzerland) - 1 Jan 1997

Lucotte G, Gérard N, Aouizérate A, Loirat F, Hazout S

Abstract excerpt

We have collected 76 parent-offspring (CAG)n values in 60 French Huntington's disease (HD) pedigrees. The analysis of intergenerational alterations in CAG repeat length shows that there is a correlation between repeat instability and parental repeat length. Paternally inherited cases are characterized by a preferential trend towards an increase in range of repeat sizes in offspring of HD patients.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA
Share to Genetic Markers
Share to Genetic Testing

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Meiosis

Share to Nerve Tissue Proteins

Share to Nuclear Proteins

Share to Repetitive Sequences, Nucleic Acid

Source

Identifiers

PMID: 9219003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Patterns of meiotic variability of the (CAG)n repeat in the Huntington disease gene.PMID 9219003Read ↗

Mitotic stability and meiotic variability of the (CAG)n repeat in the Huntington disease gene.Semantic proximity Read ↗

Parent-of-origin differences of mutant HTT CAG repeat instability in Huntington's disease.Semantic proximity Read ↗

Somatic mosaicism in sperm is associated with intergenerational (CAG)n changes in Huntington disease.Semantic proximity Read ↗

Analysis of the (CAG)n repeat causing Huntington's disease in a Mexican population.Semantic proximity Read ↗

Minimal prevalence of Huntington’s disease in the South of Brazil and instability of the expanded CAG tract during intergenerational transmissionsSemantic proximity Read ↗

Analysis of (CAG)n size heterogeneity in somatic and sperm cell DNA from intermediate and expanded Huntington disease gene carriers.Semantic proximity Read ↗

Dynamic mutation in Dutch Huntington's disease patients: increased paternal repeat instability extending to within the normal size range.Semantic proximity Read ↗

De novo expansion of a (CAG)n repeat in sporadic Huntington's disease.Semantic proximity Read ↗

The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease.Semantic proximity Read ↗

Instability of CAG repeats in Huntington's disease: relation to parental transmission and age of onset.Semantic proximity Read ↗

Increased instability of intermediate alleles in families with sporadic Huntington disease compared to similar sized intermediate alleles in the general population.Semantic proximity Read ↗

Relationship between trinucleotide repeat expansion and phenotypic variation in Huntington's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.