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Article

Saccharomyces cerevisiae PAC2 functions with CIN1, 2 and 4 in a pathway leading to normal microtubule stability.

Genetics - 1 Jul 1997

Hoyt M A, Macke J P, Roberts B T, Geiser J R

Abstract excerpt

The products of the Saccharomyces cerevisiae CIN1, CIN2 and CIN4 genes participate in a nonessential pathway required for normal microtubule function. In this article, we demonstrate that the product of PAC2 also functions in this pathway. PAC2 deletion mutants displayed phenotypes and genetic interactions similar to those caused by cin1 delta, cin2 delta and cin4 delta. These include cold-sensitive microtubule...

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PMID: 9215891
DOI: 10.1093/genetics/146.3.849
PMCID: PMC1208055

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