Article
Molecular analysis of KCNJ10 on 1q as a candidate gene for Type 2 diabetes in Pima Indians.
Diabetes - 1 Nov 2002
Farook Vidya S, Hanson Robert L, Wolford Johanna K, Bogardus Clifton, Prochazka Michal
Abstract excerpt
The KCNJ10 gene is located within a region on chromosome 1q linked to type 2 diabetes in the Pima Indians and six other populations. We therefore investigated this gene as a potential type 2 diabetes candidate gene in Pima Indians. KCNJ10 consists of two exons, spans approximately 33 kb, and we identified eight single-nucleotide polymorphisms (SNPs), including one (SNP2) in the coding region leading to a...
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