Article
Two modes of ligand binding in maltose-binding protein of Escherichia coli. Correlation with the structure of ligands and the structure of binding protein.
The Journal of biological chemistry - 11 Jul 1997
Hall J A, Gehring K, Nikaido H
Abstract excerpt
Ligands that are transported by the maltose transport system of Escherichia coli must first bind to the periplasmic maltose-binding protein (MBP). However, binding of a ligand does not always lead to its transport. As reported earlier, reduced or oxidized maltodextrins bind tightly to MBP but are...
Topics
- ATP-Binding Cassette Transporters
- Alleles
- Bacterial Proteins
- Binding Sites
- Carrier Proteins
- Cloning, Molecular
- Cyclodextrins
- DNA, Bacterial
- Escherichia coli
- Escherichia coli Proteins
- Ligands
- Maltose
- Maltose-Binding Proteins
- Models, Chemical
- Monosaccharide Transport Proteins
- Periplasmic Binding Proteins
- Protein Binding
- Protein Conformation