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Article

Synthesis and hydrolysis of cyclic ADP-ribose by human leukocyte antigen CD38: inhibition of hydrolysis by ATP and physiological significance.

Methods in enzymology - 1 Jan 1997

Okamoto H, Takasawa S, Tohgo A, Nata K, Kato I, Noguchi N

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Share to Adenosine Diphosphate Ribose
Share to ADP-ribosyl Cyclase
Share to ADP-ribosyl Cyclase 1
Share to Antigens, Differentiation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Insulin Secretion

Share to N-Glycosyl Hydrolases

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Identifiers

PMID: 9211326
DOI: 10.1016/s0076-6879(97)80122-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

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Synthesis and hydrolysis of cyclic ADP-ribose by human leukocyte antigen CD38: inhibition of hydrolysis by ATP and physiological significance.PMID 9211326Read ↗

The Pharmacology of CD38/NADase: An Emerging Target in Cancer and Diseases of AgingSemantic proximity Read ↗

Deletion of CD38 enhances CD19 chimeric antigen receptor T cell functionSemantic proximity Read ↗

The enzymatic activities of CD38 enhance CLL growth and trafficking: implications for therapeutic targeting.Semantic proximity Read ↗

Mechanism of cyclizing NAD to cyclic ADP-ribose by ADP-ribosyl cyclase and CD38.Semantic proximity Read ↗

Role of the human CD38 molecule in B cell activation and proliferation.Semantic proximity Read ↗

A novel mechanism for coupling cellular intermediary metabolism to cytosolic Ca2+ signaling via CD38/ADP-ribosyl cyclase, a putative intracellular NAD+ sensor.Semantic proximity Read ↗

Acidic residues at the active sites of CD38 and ADP-ribosyl cyclase determine nicotinic acid adenine dinucleotide phosphate (NAADP) synthesis and hydrolysis activities.Semantic proximity Read ↗

Overexpression of human CD38/ADP-ribosyl cyclase enhances acetylcholine-induced Ca2+ signalling in rodent NG108-15 neuroblastoma cells.Semantic proximity Read ↗

Structural basis for enzymatic evolution from a dedicated ADP-ribosyl cyclase to a multifunctional NAD hydrolase.Semantic proximity Read ↗

Mice deficient for the ecto-nicotinamide adenine dinucleotide glycohydrolase CD38 exhibit altered humoral immune responses.Semantic proximity Read ↗

[Mechanistic insight into hydrolysis of oxidized nucleotide diphosphates by human NUDT5].Semantic proximity Read ↗

Measurement of the ADP:ATP ratio in human leukaemic cell lines can be used as an indicator of cell viability, necrosis and apoptosisSemantic proximity Read ↗

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