HLA molecules, bacteria and autoimmunity

Abstract excerpt

It has been well established that many diseases are linked to HLA antigens. Two of the most interesting HLA associations may provide some insight into the pathogenesis of rheumatic inflammatory conditions. In ankylosing spondylitis (AS), 96% of patients possess HLA-B27, whilst the frequency of this marker in the general population is c. 8%. In rheumatoid arthritis (RA), >90% of patients possess either HLA-DR1 or...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Rheumatoid Arthritis Research and Therapies
• Share to Spondyloarthritis Studies and Treatments
• Share to Systemic Lupus Erythematosus Research